Welcome to the King Laboratory
Cellular Metabolite Sensing
Simon Fraser University, Burnaby, BC
Department of Molecular Biology and Biochemistry, Since July 2022
Who we are
We are an interdisciplinary team of researchers that work together to tackle important problems in organismal metabolite sensing.
What we do
Organisms ‘sense’ chemical messages to adapt to their surroundings. We are focused on decoding how these messages are sensed by cells to trigger adaptive responses. One area our team is particularly interested in is how organisms sense the essential biological gas CO₂. Our group develops proteomic methods to uncover proteins that are modified by CO₂ to trigger cellular pathways. We then study the underlying molecular basis using targeted biochemistry and structural biology experiments.
Why we do it
Our goal is to contribute toward developing new antibacterial therapies. Further, we envision that knowledge generated from our research will enable engineering CO₂-fixing microorganisms to develop sustainable biotechnologies that promote a green economy and combat climate change.
Interested in joining?
Interested in molecular microbiology research? A new lab is a great place to build skills and develop as a scientist.